Article

Self-organizing actin networks drive sequential endocytic protein recruitment and vesicle release on synthetic lipid bilayers

2023-02-14

Abstract excerpt

Forces generated by actin assembly assist membrane invagination during clathrin-mediated endocytosis (CME). The sequential recruitment of core endocytic proteins and regulatory proteins, and assembly of the actin network, are well documented in live cells and are highly conserved from yeasts to humans. However, understanding of CME protein self-organization, as well as the biochemical and mechanical principles tha...

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Literature Corpus work: a0372260-6c7a-5ad0-97d0-7436e52340c8
DOI: 10.1101/2023.02.14.528546

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