Article
Clathrin exchange during clathrin-mediated endocytosis.
The Journal of cell biology - 15 Oct 2001
Wu X, Zhao X, Baylor L, Kaushal S, Eisenberg E, Greene L E
Abstract excerpt
During clathrin-mediated endocytosis, clathrin-coated pits invaginate to form clathrin-coated vesicles (CVs). Since clathrin-coated pits are planar structures, whereas CVs are spherical, there must be a structural rearrangement of clathrin as invagination occurs. This could occur through simple addition of clathrin triskelions to the edges of growing clathrin-coated pits with very little exchange occurring...
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