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Article

Generation and applications of MADM-based mouse genetic mosaic system.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2014

Zong Hui

Abstract excerpt

Genetic mosaics describe organisms that contain cells with distinct genotypes related to somatic transposition, mitotic recombination, or genomic aberrations. Most, if not all, human cancers are genetic mosaics because cancer cells bear mutations that are absent in normal cells within the same body. While naturally occurring mutant cells in genetic mosaic animals are difficult to track down, a genetically...

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PMID: 25064104
DOI: 10.1007/978-1-4939-1215-5_10

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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