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Article

Mosaic analysis with double markers (MADM) in mice.

Cold Spring Harbor protocols - 1 Feb 2014

Espinosa J Sebastian, Tea Joy S, Luo Liqun

Abstract excerpt

The human brain comprises more than 100 billion neurons, each of which has an elaborate shape and a complex pattern of connections. To untangle this complexity, it is often useful to visualize one neuron at a time. Mosaic analysis with double markers (MADM) is a genetic method for labeling and manipulating individual neurons. This method was developed in mice and it allows simultaneous labeling and gene knockout...

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Identifiers

PMID: 24492775
DOI: 10.1101/pdb.prot080366

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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