Article
Inducing segmental aneuploid mosaicism in the mouse through targeted asymmetric sister chromatid event of recombination.
Genetics - 1 Sept 2008
Duchon Arnaud, Besson Vanessa, Pereira Patricia Lopes, Magnol Laetitia, Hérault Yann
Abstract excerpt
Loss or gain of whole chromosomes, or parts of chromosomes, is found in various pathological conditions, such as cancer and aneuploidy, and results from the missegregation of chromosomes during cellular division or abnormal mitotic recombination. We introduce a novel strategy for determining the...
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