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Article

Overexpression of Reelin prevents the manifestation of behavioral phenotypes related to schizophrenia and bipolar disorder.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Nov 2011

Teixeira Cátia M, Martín Eduardo D, Sahún Ignasi, Masachs Nuria, Pujadas Lluís, Corvelo André, Bosch Carles, Rossi Daniela, Martinez Albert, Maldonado Rafael, Dierssen Mara, Soriano Eduardo

Abstract excerpt

Despite the impact of schizophrenia and mood disorders, which in extreme cases can lead to death, recent decades have brought little progress in the development of new treatments. Recent studies have shown that Reelin, an extracellular protein that is critical for neuronal development, is reduced in schizophrenia and bipolar disorder patients. However, data on a causal or protective role of Reelin in psychiatric...

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Identifiers

PMID: 21814183
DOI: 10.1038/npp.2011.153
PMCID: PMC3194085

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Source receipt: pubmed, retrieved 7 Sept 2026.

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