Article

KICA: A MATLAB package for high-throughput analysis of calcium and voltage imaging data from cardiac cells

2025-07-17

Abstract excerpt

<h4>Background: </h4> Fluorescent time-series data reporting cellular calcium homeostasis and membrane voltage are common measures of cardiac physiology with widespread utility in areas such as disease modelling and drug screening. The growth in the use of high-throughput platforms in this area has resulted in a significantly increased requirement for automated quality control, processing and data analysis. Method...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 56a33f4c-7fc4-5ff3-a0cd-e68aa6ed0879
DOI: 10.12688/f1000research.166855.1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

KICA: A MATLAB package for high-throughput analysis of calcium and voltage imaging data from cardiac cellsDOI 10.12688/f1000research.166855.1Read

High Throughput Measurement of Ca++ Dynamics in Human Stem Cell-Derived Cardiomyocytes by Kinetic Image Cytometery: A Cardiac Risk Assessment Characterization Using a Large Panel of Cardioactive and Inactive Compounds.Semantic proximity Read

Arrhythpy: An Automated Tool to Quantify and Classify Arrhythmias in Ca <sup>2+</sup> Transients of iPSC-CardiomyocytesSemantic proximity Read

Sinusoidal voltage protocols for rapid characterisation of ion channel kineticsSemantic proximity Read

CellSpecks: A Software for Automated Detection and Analysis of Calcium Channels in Live CellsSemantic proximity Read

Four ways to fit an ion channel modelSemantic proximity Read

Computational tool to study perturbations in muscle regulation and its application to heart diseaseSemantic proximity Read

Fast-Response Calmodulin-Based Fluorescent Indicators Reveal Rapid Intracellular Calcium Dynamics.Semantic proximity Read

Resolving artefacts in voltage-clamp experiments with computational modelling: an application to fast sodium current recordingsSemantic proximity Read

Imaging cellular signals in the heart <i>in vivo</i> : Cardiac expression of the high-signal Ca <sup>2+</sup> indicator GCaMP2Semantic proximity Read

Computational Tool to Study Perturbations in Muscle Regulation and Its Application to Heart Disease.Semantic proximity Read

Novel algorithms for improved detection and analysis of fluorescent signal fluctuationsSemantic proximity Read

Computational biology in the study of cardiac ion channels and cell electrophysiology.Semantic proximity Read