Article

Cellular mechanisms of heterogeneity in <i>NF2</i> -mutant schwannoma

2021-01-03

Abstract excerpt

Schwannomas are common sporadic nervous system tumors and diagnostic features of familial neurofibromatosis type 2 (NF2) that develop predominantly on cranial and spinal nerves and cause severe neurological deficits and significant morbidity. Virtually all schwannomas result from inactivation of the NF2 tumor suppressor gene with few, if any, cooperating mutations. Despite their genetic uniformity schwannomas exh...

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Literature Corpus work: 56677509-c025-5be0-93e8-5abf2938a6d2
DOI: 10.1101/2020.12.31.424999

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