Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dissecting Clinical Heterogeneity in Neurofibromatosis Type 1

24 Jan 2017

Abstract excerpt

Neurofibromatosis type 1 (NF1) is a common neurogenetic disorder in which affected children and adults are predisposed to the development of benign and malignant nervous system tumors. Caused by a germline mutation in the NF1 tumor suppressor gene, individuals with NF1 are prone to optic gliomas, malignant gliomas, neurofibromas, and malignant peripheral nerve sheath tumors, as well as behavioral, cognitive,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Neuroblastoma Research and Treatments
Share to Neurofibromatosis and Schwannoma Cases
Share to Sarcoma Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28135565
DOI: 10.1146/annurev-pathol-052016-100228

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dissecting Clinical Heterogeneity in Neurofibromatosis Type 1PMID 28135565Read ↗

Clinical features and pathobiology of neurofibromatosis 1.Semantic proximity Read ↗

Updated nomenclature for human and mouse neurofibromatosis type 1 genesSemantic proximity Read ↗

Genetic and non-genetic factors influencing phenotypic variability in neurofibromatosis type 1.Semantic proximity Read ↗

NeurofibromatosisSemantic proximity Read ↗

Neurofibromatosis, Phenotype, Natural History, and PathogenesisSemantic proximity Read ↗

Guidelines for the diagnosis and management of individuals with neurofibromatosis 1.Semantic proximity Read ↗

NF1germline mutation differentially dictates optic glioma formation and growth in neurofibromatosis-1Semantic proximity Read ↗

Recent Advances in the Diagnosis and Pathogenesis of Neurofibromatosis Type 1 (NF1)-associated Peripheral Nervous System Neoplasms.Semantic proximity Read ↗

Impacts of NF1 Gene Mutations and Genetic Modifiers in Neurofibromatosis Type 1Semantic proximity Read ↗

Neurofibromatosis.Semantic proximity Read ↗

Neurofibromatosis Type 1 RevisitedSemantic proximity Read ↗

Phenotypic heterogeneity of neurofibromatosis type 1 in a large international registry.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.