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High-Dimensional Imaging of Vestibular Schwannoma Reveals Distinctive Immunological Networks Across Histomorphic Niches in <i>NF2</i> -related Schwannomatosis

2024-04-12

Abstract excerpt

NF2 -related Schwannomatosis ( NF2 SWN) is a rare tumour-predisposition syndrome characterised by the growth of multiple central and peripheral nervous system neoplasms. The drivers of NF2 SWN are pathogenic variants in the tumour suppressor gene NF2 , encoding the protein Merlin, leading to development of bilateral vestibular schwannoma (VS) in >95% of patients. VS tumours are characterised by infiltration of...

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Literature Corpus work
86e8a75a-99d6-52dd-a52e-a66d7458ab2d
DOI
10.1101/2024.04.09.588593
Open publication

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High-Dimensional Imaging of Vestibular Schwannoma Reveals Distinctive Immunological Networks Across Histomorphic Niches in <i>NF2</i> -related SchwannomatosisDOI 10.1101/2024.04.09.588593
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