Article

Stochastic modeling of a gene regulatory network driving B cell development in germinal centers

2023-04-01

Abstract excerpt

Germinal centers (GCs) are the key histological structures of the adaptive immune system, responsible for the development and selection of B cells producing high-affinity antibodies against antigens. Due to their level of complexity, unexpected malfunctioning may lead to a range of pathologies, including various malignant formations. One promising way to improve the understanding of malignant transformation is to...

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Literature Corpus work: 56432742-9c33-515e-aa64-eb6136340f6b
DOI: 10.1101/2023.03.29.534713

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