Article
Classifying Germinal Center Derived Lymphomas—Navigate a Complex Transcriptional Landscape
14 Jul 2022
Abstract excerpt
Classification of lymphoid neoplasms is based mainly on histologic, immunologic, and (rarer) genetic features. It has been supplemented by gene expression profiling (GEP) in the last decade. Despite the considerable success, particularly in associating lymphoma subtypes with specific transcriptional programs and classifier signatures of up- or downregulated genes, competing molecular classifiers were often...
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