Article

<i>ATP13A3</i> Variants Promote Pulmonary Arterial Hypertension by Disrupting Polyamine Transport

2023-08-29

Abstract excerpt

<h4>Aims</h4> Potential loss-of-function variants of ATP13A3 , the gene encoding a P5B-type transport ATPase of undefined function, were recently identified in pulmonary arterial hypertension (PAH) patients. ATP13A3 is implicated in polyamine transport but its function has not been fully elucidated. Here, we sought to determine the biological function of ATP13A3 in vascular endothelial cells and how PAH-associat...

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Literature Corpus work: 56072464-4a8e-5a4a-9696-3f8c46eb29ff
DOI: 10.1101/2023.08.29.554603

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