Article

Characterising ATP13A3 biological function and its role in pulmonary arterial hypertension

2020-01-01

Abstract excerpt

Pulmonary arterial hypertension (PAH) is a rare but devastating disease characterised by the progressive remodelling of the small pulmonary vessels. Although the causes may vary, similar pathobiological features are shared among different forms of PAH, with endothelial dysfunction, the hyperproliferation of smooth muscle cells and mesenchymal cells in the vascular wall, as well as inflammation contributing to this...

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Literature Corpus work: ced2aa03-e07c-54ca-ac07-e5e8e37e7858
DOI: 10.17863/cam.60622

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