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Attenuated adenosine mediated immune-dampening increases natural killer cell activity in early age-related macular degeneration

2025-01-25

Abstract excerpt

<h4>ABSTRACT</h4> Non-exudative age-related macular degeneration (AMD) involves retinal pigment epithelium (RPE) dysfunction and has been linked to altered intraocular immunity. Our investigation focuses on immune cell subsets and inflammation-associated factors in the eyes with early and intermediate AMD. We observed elevated levels of activated natural killer (NK) cells and interferon-γ, concurrent with reduced...

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Literature Corpus work
55cdc14c-29ce-577b-86ad-d414a60fe1d4
DOI
10.1101/2025.01.22.634301
Open publication

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Attenuated adenosine mediated immune-dampening increases natural killer cell activity in early age-related macular degenerationDOI 10.1101/2025.01.22.634301
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