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Article

Transcriptome Analysis on Monocytes from Patients with Neovascular Age-Related Macular Degeneration

4 Jul 2016

Abstract excerpt

Mononuclear phagocytes (MPs), including monocytes/macrophages, play complex roles in age-related macular degeneration (AMD) pathogenesis. We reported altered gene-expression signature in peripheral blood mononuclear cells from AMD patients, and a chemokine receptor signature on AMD monocytes. To obtain comprehensive understanding of MP involvement, particularly in peripheral circulation in AMD, we performed...

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PMID: 27374485
DOI: 10.1038/srep29046

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