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Single-cell profiling identifies a CD8<sup>bright</sup>CD244<sup>bright</sup>Natural Killer cell subset that reflects disease activity in HLA-A29-positive<i>birdshot chorioretinopathy</i>

2022-09-15

Abstract excerpt

<h4>ABSTRACT</h4> Birdshot chorioretinopathy uveitis (BCR-UV) is strongly associated with HLA-A29 which implicates MHC-I pathway mediated perturbation of natural killer (NK) cells as a potential disease mechanism. We profiled blood NK cells at single-cell resolution in a cohort of patients and healthy controls and investigated the links between NK cell subpopulations and disease activity. Flow cytometry analysis o...

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Literature Corpus work
bec2ee4c-e082-5b84-a71f-03b42b13f23a
DOI
10.1101/2022.09.11.22279821
Open publication

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Single-cell profiling identifies a CD8<sup>bright</sup>CD244<sup>bright</sup>Natural Killer cell subset that reflects disease activity in HLA-A29-positive<i>birdshot chorioretinopathy</i>DOI 10.1101/2022.09.11.22279821
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