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Article

Dynamic interplay of innate and adaptive immunity during sterile retinal inflammation: Insights from the transcriptome

2018-02-24

Abstract excerpt

The pathogenesis of many retinal degenerations, such as age-related macular degeneration (AMD), is punctuated by an ill-defined network of sterile inflammatory responses. The delineation of innate and adaptive immune milieu amongst the broad leukocyte infiltrate, and the gene networks which construct these responses, are poorly described in the eye. Using photo-oxidative damage in a rodent model of subretinal infl...

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Literature Corpus work
ad02a2cd-16cf-5d16-8810-32c4d1c998c4
DOI
10.1101/267757
Open publication

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