Article

Determining the Mutation Bias of Favipiravir in Influenza Using Next-generation Sequencing

2018-07-23

Abstract excerpt

Favipiravir is a broad spectrum antiviral drug that may be used to treat influenza. Previous research has identified that favipiravir likely acts as a mutagen but the precise mutation bias that favipiravir induces in influenza virus RNAs has not been described. Here, we use next-generation sequencing (NGS) with barcoding of individual RNA molecules to accurately and quantitatively detect favipiravir-induced mutati...

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Literature Corpus work: 55b8fa12-6e0c-58fa-a670-f35d0cf33a5b
DOI: 10.1101/375378

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