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Article

Applications of Deep Mutational Scanning in Virology.

Viruses - 28 May 2021

Burton Thomas D, Eyre Nicholas S

Abstract excerpt

Several recently developed high-throughput techniques have changed the field of molecular virology. For example, proteomics studies reveal complete interactomes of a viral protein, genome-wide CRISPR knockout and activation screens probe the importance of every single human gene in aiding or fighting a virus, and ChIP-seq experiments reveal genome-wide epigenetic changes in response to infection. Deep mutational...

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Identifiers

PMID: 34071591
DOI: 10.3390/v13061020
PMCID: PMC8227372

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