Article

Human Lymph Node Cellular Senescence Atlas Reveals Age-Dependent Alteration in Germinal Center B Cell Function and Niches

2026-04-06

Abstract excerpt

<h4>SUMMARY</h4> Immunosenescence, the age-associated decline in immune function, is a key feature of human aging. In human lymphoid organs, however, the specific immune cell populations that acquire senescence-associated phenotypes during aging and how they influence the surrounding tissue microenvironment remain poorly understood. A spatially resolved map of these senescence-associated immune states in human ly...

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Literature Corpus work: 55b57d60-2204-5bfc-b7de-64b378c21f46
DOI: 10.64898/2026.04.02.716161

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