Article

Senescence phenotype of lymph node stromal cells from patients with rheumatoid arthritis is partly restored by dasatinib treatment

2023-12-11

Abstract excerpt

<h4>Objective</h4> Cellular senescence is a state of proliferation arrest of cells occurring during aging. The persistence and accumulation of senescent cells has been implicated in the pathogenesis of age-related diseases like rheumatoid arthritis (RA). RA is a chronic autoimmune disease in which loss of immune tolerance and systemic autoimmunity precedes clinical onset of disease. Lymph node stromal cells (LNSC...

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Literature Corpus work: 12c517ab-59fd-5539-9831-61b29af093f2
DOI: 10.1101/2023.12.10.571042

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