Article

Clustering based approach for population level identification of condition-associated T-cell receptor β-chain CDR3 sequences

2018-12-07

Abstract excerpt

<h4>Motivation</h4> Deep immune receptor sequencing, Repseq, provides unprecedented opportunities to identify condition-associated T-cell clones, represented by T-cell receptor (TCR) CDR3 sequences. TCR profiling has potential value for increasing immunopathological understanding of various diseases, and holds considerable clinical relevance. However, due to the immense diversity of the immune repertoire, identif...

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Literature Corpus work: 55ae9505-b75b-5f2f-8b16-87c529c28d1d
DOI: 10.1101/490102

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