Article

Early suppression of excitability in subcortical band heterotopia modifies epileptogenesis in rats

2022-09-08

Abstract excerpt

Malformations of cortical development represent a major cause of epilepsy in childhood. However, the pathological substrate and dynamic changes leading to the development and progression of epilepsy remain unclear. Here, we characterized an etiology-relevant rat model of subcortical band heterotopia (SBH), a diffuse type of cortical malformation associated with drug-resistant seizures in humans. We used longitudin...

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Literature Corpus work: 5599b1fe-4b61-5d95-85fc-a095d9915bc0
DOI: 10.1101/2022.09.06.506850

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