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Long-term hippocampal low-frequency stimulation alleviates focal seizures, memory deficits and synaptic pathology in epileptic mice

2025-01-20

Abstract excerpt

<h4>Background</h4> Mesial temporal lobe epilepsy (MTLE) is a prevalent form of focal epilepsy characterized by seizures originating from the hippocampus and adjacent regions. Neurostimulation presents an alternative for surgery-ineligible patients with intractable seizures. However, conventional approaches have limited efficacy and require refinement for better seizure control. While hippocampal low-frequency st...

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Literature Corpus work
59a3a28d-525d-59e3-987c-c1f4ed193452
DOI
10.1101/2025.01.16.633322
Open publication

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Long-term hippocampal low-frequency stimulation alleviates focal seizures, memory deficits and synaptic pathology in epileptic miceDOI 10.1101/2025.01.16.633322
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