Article

New Insights into Epileptic Spasm Generation and Treatment from the TTX Animal Model

2025-02-26

Abstract excerpt

<h4>Summary</h4> Currently, we have an incomplete understanding of the mechanisms underlying infantile epileptic spasms syndrome (IESS). However, over the past decade, significant efforts have been made to develop IESS animal models to provide much-needed mechanistic information for therapy development. Our laboratory has focused on the TTX model, in which tetrodotoxin (TTX) is infused into the neocortex of infan...

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Literature Corpus work: 2e501d77-c45a-5f6d-b9ed-b9a91e1bfe48
DOI: 10.1101/2025.02.25.639129

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