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Article

Basic mechanisms of catastrophic epilepsy -- overview from animal models.

Brain & development - 1 Sept 2013

Galanopoulou Aristea S

Abstract excerpt

Infantile spasms are age-specific seizures of infantile epileptic encephalopathies that are usually associated with poor epilepsy and neurodevelopmental outcomes. The current treatments are not always effective and may be associated with significant side effects. Various mechanisms have been proposed as pathogenic for infantile spasms, including cortical or brainstem dysfunction, disruption of normal...

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Identifiers

PMID: 23312951
DOI: 10.1016/j.braindev.2012.12.005
PMCID: PMC3644363

Genes

CRH
ARX

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