Article

Chikungunya virus infection disrupts lymph node lymphatic endothelial cell composition and function via MARCO

2023-10-13

Abstract excerpt

<h4>ABSTRACT</h4> Infection with chikungunya virus (CHIKV) causes disruption of draining lymph node (dLN) organization, including paracortical relocalization of B cells, loss of the B cell-T cell border, and lymphocyte depletion that is associated with infiltration of the LN with inflammatory myeloid cells. Here, we find that during the first 24 h of infection, CHIKV RNA accumulates in MARCO-expressing lymphatic...

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Literature Corpus work: 558c1c17-736f-553f-87f6-fb3f4d114f3f
DOI: 10.1101/2023.10.12.561615

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