Article

Ebola’s Hidden Target: Virus Transmission to and Accumulation within Skin

2025-04-04

Abstract excerpt

<h4>ABSTRACT</h4> Ebola virus (EBOV), the causative agent of Ebola virus disease (EVD), remains one of WHO’s top ten threats to global health. Infectious EBOV virions can be found on the surface of skin late during systemic infection and passed from the deceased through skin-to-skin contact. Here, we assess viral load and antigen expression in the skin of EBOV-infected non-human primates (NHP) and mouse adapted-E...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 0bdd156a-c06a-5664-9187-00b1d73b1c28
DOI: 10.1101/2025.04.04.647113

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Ebola’s Hidden Target: Virus Transmission to and Accumulation within SkinDOI 10.1101/2025.04.04.647113Read

TIM-1 serves as a receptor for Ebola virus in vivo, enhancing viremia and pathogenesisSemantic proximity Read

Understanding the pathogenesis of uveitis in Ebola virus disease survivors: a study protocol for clinical, molecular virologic, and immunologic characterizationSemantic proximity Read

Herpes Simplex Virus Assembly and Spread in murine skin after infection from the outsideSemantic proximity Read

Pan-viral protection against arboviruses by targeting inoculation site-based skin macrophagesSemantic proximity Read

Anti-Ebola virus mAb 3A6 with unprecedented potency protects highly viremic animals from fatal outcome and physically lifts its glycoprotein target from the virion membraneSemantic proximity Read

A Mouse Upper Respiratory Tract Coronavirus Infection Model with OC43 Defines Toll-Like Receptor 2/6 Mediated Innate Immune ProtectionSemantic proximity Read

Mapping of susceptibility loci for Ebola virus pathogenesis in mice.Semantic proximity Read

The Secret Life of Viral Entry Glycoproteins: Moonlighting in Immune EvasionSemantic proximity Read

Advances and Challenges in Molecular Imaging of Viral InfectionsSemantic proximity Read

Tick extracellular vesicles alter keratinocyte function in the skin epidermisSemantic proximity Read

Single-cell characterization of skin response to a bite by West Nile virus-infected mosquito reveals fibroblast-mediated barrier to transmissionSemantic proximity Read

Characterization of Human Immortalized Keratinocyte Cells Infected by Monkeypox VirusSemantic proximity Read