Article

Single-cell mapping reveals new markers and functions of lymphatic endothelial cells in lymph nodes

2020-01-09

Abstract excerpt

<h4>ABSTRACT</h4> Lymph nodes (LNs) are highly organized secondary lymphoid organs that mediate adaptive immune responses to antigens delivered via afferent lymphatic vessels. Lymphatic endothelial cells (LECs) line intranodal lymphatic sinuses and organize lymph and antigen distribution. LECs also directly regulate T cells, mediating peripheral tolerance to self-antigens, and play a major role in many diseases i...

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Literature Corpus work: 36e75fda-58ed-5442-9fc2-7470c49a0cfa
DOI: 10.1101/2020.01.09.900241

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