Article

Chikungunya virus infection disrupts MHC-I antigen presentation via nonstructural protein 2

2023-11-04

Abstract excerpt

<h4>ABSTRACT</h4> Infection by chikungunya virus (CHIKV), a mosquito-borne alphavirus, causes severe polyarthralgia and polymyalgia, which can last in some people for months to years. Chronic CHIKV disease signs and symptoms are associated with the persistence of viral nucleic acid and antigen in tissues. Like humans and nonhuman primates, CHIKV infection in mice results in the development of robust adaptive anti...

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Literature Corpus work: 4cfecf34-4819-5973-928a-041a8568bf7e
DOI: 10.1101/2023.11.03.565436

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