Article

Novel start codons introduce novel coding sequences in the human genomes

2020-11-05

Abstract excerpt

Start-gain mutations can introduce novel start codons and generate novel coding sequences that may affect the function of genes. In this study, we systematically investigated the novel start codons that were either polymorphic or fixed in the human genomes. 829 polymorphic start-gain SNVs were identified in the human populations, and the novel start codons introduced by these SNVs have significantly higher activit...

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Literature Corpus work: 54fcd0b1-a8e7-55bb-82c1-f2b7bb510987
DOI: 10.1101/2020.11.04.368936

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