Article
Screening of Kozak-motif-located SNPs and analysis of their association with human diseases.
Biochemical and biophysical research communications - 29 Jan 2010
Xu Heng, Wang Ping, You Jin, Zheng Yufang, Fu Yujie, Tang Quan, Zhou Li, Wei Zejun, Lin Bin, Shu Yang, Zhu Yufei, Hu Landian, Kong Xiangyin
Abstract excerpt
The Kozak motif, which is located near the translational start codon, often regulates the protein translation. Moreover, it is believed that the conserved positions -3 and +4 contribute the most. Since changes that occur in this motif have a great impact on protein yield and in some cases are ass...
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