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The role of BST‐2/Tetherin in host protection and disease manifestation

7 Dec 2015

Abstract excerpt

Host cells respond to viral infections by activating immune response genes that are not only involved in inflammation, but may also predispose cells to cancerous transformation. One such gene is BST-2, a type II transmembrane protein with a unique topology that endows it tethering and signaling potential. Through this ability to tether and signal, BST-2 regulates host response to viral infection either by...

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PMID: 27042298
DOI: 10.1002/iid3.92

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