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Article

Impact of cellular restriction gene (TRIM5α, BST-2) polymorphisms on the acquisition of HIV-1 and disease progression.

The journal of gene medicine - 1 Feb 2018

Singh HariOm, Samani Dharmesh, Ghate Manisha V, Gangakhedkar Raman R

Abstract excerpt

BACKGROUND: TRIM5α and BST-2 are cellular restriction factors affecting the HIV-1 infection and its progression. Genetic variability in these genes alters the expression pattern. Hence, we aimed to examine the impact of the TRIM5α (rs10838525, rs7127617 and rs904375) and BST2 (rs3217318 and rs71694748) polymorphisms on the acquisition of HIV-1 and its progression. METHODS: Genotyping of TRIM5α and BST-2...

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Identifiers

PMID: 29282802
DOI: 10.1002/jgm.3004

Genes

BST2

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