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Interdependent Dynamics of mRNA Expression and HIV-1 Viral Load: Insights from Transcriptomics and Mendelian Randomization

2025-11-14

Abstract excerpt

<h4>ABSTRACT</h4> The interaction between HIV-1 and the host immune system plays a crucial role in the natural control and progression of the infection. Previous studies have identified APOBEC3G, Tetherin, SAMHD1, and SERINC5 as HIV-1 host restriction factors, which are counteracted by the viral proteins Vif, Vpu, and Nef, respectively. The blood expression levels of some of these host proteins are correlated wit...

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Literature Corpus work
f0ab149e-02dc-5ce2-95a4-02365b54b86f
DOI
10.1101/2025.11.13.688267
Open publication

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Interdependent Dynamics of mRNA Expression and HIV-1 Viral Load: Insights from Transcriptomics and Mendelian RandomizationDOI 10.1101/2025.11.13.688267
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