Article
Natural killer cell developmental pathways: a question of balance.
Annual review of immunology - 1 Jan 2006
Di Santo James P
Abstract excerpt
NK cells sit at the crossroads of innate and adaptive immunity and help coordinate tumor immunosurveillance and the immune response against pathogens. Balancing signals to NK cell precursors is crucial for their early development, when transcription factors compete to specify the different lymphocyte subsets. Despite an elaborate schema for NK cell development and differentiation, several major issues remain to...
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