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Article

The breast tumor microenvironment alters the phenotype and function of natural killer cells.

Cellular & molecular immunology - 1 Sept 2016

Krneta Tamara, Gillgrass Amy, Chew Marianne, Ashkar Ali A

Abstract excerpt

Natural killer (NK) cells are innate immune cells with the ability to identify and eliminate transformed cells. However, within tumors, many studies have described NK cells as non-functional. The developmental stage of tumor-associated NK cells and how this may relate to functionality has not been explored. We examined the developmental state of NK cells from polyoma middle T antigen (pyMT) transgenic mouse...

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Identifiers

PMID: 26277898
DOI: 10.1038/cmi.2015.42
PMCID: PMC5037278

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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