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Article

Natural killer cell development and maturation in aged mice.

Mechanisms of ageing and development - 1 Jan 2014

Beli Eleni, Duriancik David M, Clinthorne Jonathan F, Lee Taehyung, Kim Sungjin, Gardner Elizabeth M

Abstract excerpt

The effect of aging on natural killer cell homeostasis is not well studied in humans or in animal models. We compared natural killer (NK) cells from young and aged mice to investigate age-related defects in NK cell distribution and development. Our findings indicate aged mice have reduced NK cells in most peripheral tissues, but not in bone marrow. Reduction of NK cells in periphery was attributed to a reduction...

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Identifiers

PMID: 24361677
DOI: 10.1016/j.mad.2013.11.007
PMCID: PMC4043280

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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