Article

COX6A2 deficiency leads to cardiac remodeling in human pluripotent stem cell-derived cardiomyocytes

2023-02-17

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Cardiac remodeling is the initiating factor in the development of heart failure(HF), which can occur in various cardiomyopathies. cytochrome c oxidase subunit 6A2(COX6A2) is one of the components of cytochrome c oxidase, which drives oxidative phosphorylation. The pathogenesis of myocardial remodeling caused by COX6A2 deficiency in humans remains unclear due to...

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Literature Corpus work: 5440ad72-1b8e-5c9c-8b8e-f1018bd03644
DOI: 10.21203/rs.3.rs-2165236/v1

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