Article
Modeling Cardiovascular Diseases with Patient-Specific Human Pluripotent Stem Cell-Derived Cardiomyocytes.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2016
Burridge Paul W, Diecke Sebastian, Matsa Elena, Sharma Arun, Wu Haodi, Wu Joseph C
Abstract excerpt
The generation of cardiomyocytes from human induced pluripotent stem cells (hiPSCs) provides a source of cells that accurately recapitulate the human cardiac pathophysiology. The application of these cells allows for modeling of cardiovascular diseases, providing a novel understanding of human disease mechanisms and assessment of therapies. Here, we describe a stepwise protocol developed in our laboratory for the...
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