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Article

Human heart disease: lessons from human pluripotent stem cell-derived cardiomyocytes.

Cellular and molecular life sciences : CMLS - 1 Oct 2017

Giacomelli E, Mummery C L, Bellin M

Abstract excerpt

Technical advances in generating and phenotyping cardiomyocytes from human pluripotent stem cells (hPSC-CMs) are now driving their wider acceptance as in vitro models to understand human heart disease and discover therapeutic targets that may lead to new compounds for clinical use. Current literature clearly shows that hPSC-CMs recapitulate many molecular, cellular, and functional aspects of human heart...

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Identifiers

PMID: 28573431
DOI: 10.1007/s00018-017-2546-5
PMCID: PMC5597692

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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