Article

Paralog-dependent Specialization of Paf1C subunit, Ctr9, for Sex Chromosome Gene Regulation and Male Germline Differentiation in Drosophila

2024-04-26

Abstract excerpt

Testis-specific gene regulatory mechanisms govern the differentiation of germ cells into mature sperms. However, the molecular underpinnings are not fully elucidated. Here, we show the subunits forming Polymerase Associated Factor 1 Complex (Paf1C), a transcription regulator conserved across eukaryotes, have their individual paralogs predominantly expressed in Drosophila testes. One of these, namely, Ctr9 paralog...

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Literature Corpus work: 162d446c-7f8c-5663-bf9e-939b15ed7e7c
DOI: 10.1101/2024.04.23.590698

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