Article

LMWF5A suppresses cytokine release by modulating select inflammatory transcription factor activity in stimulated PBMC

2020-10-06

Abstract excerpt

<h4>Background: </h4> Dysregulation of transcription and cytokine expression has been implicated in the pathogenesis of a variety inflammatory diseases. The resulting imbalance between inflammatory and resolving transcriptional programs can cause an overabundance of pro-inflammatory, classically activated macrophage type 1 (M1) and/or helper T cell type 1 (Th1) products, such as IFNγ, TNFα, IL1-β, and IL12, that p...

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Identifiers and source

Literature Corpus work: 539d4a15-49f7-51c7-b32c-97c12d31d2fb
DOI: 10.21203/rs.3.rs-86515/v1

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