Article

<i>In vitro</i> Targeting of Transcription Factors to Control the Cytokine Release Syndrome in COVID-19

2020-12-30

Abstract excerpt

Treatment of the cytokine release syndrome (CRS) has become an important part of rescuing hospitalized COVID-19 patients. Here, we systematically explored the transcriptional regulators of inflammatory cytokines involved in the COVID-19 CRS to identify candidate transcription factors (TFs) for therapeutic targeting using approved drugs. We integrated a resource of TF-cytokine gene interactions with single-cell RNA...

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Literature Corpus work: 8a539e3c-8146-5977-bc36-97613f28ef58
DOI: 10.1101/2020.12.29.424728

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