Article

Temporal Mapping of Radiation-Induced Neural Injury and Mitigation in Human Cortical Organoids

2026-03-06

Abstract excerpt

<h4>Background</h4> Radiation therapy is a standard-of-care oncological treatment for central nervous system (CNS) malignancies. However, as survival outcomes improve, radiation-induced injury to normal brain tissue has increased in clinical significance. CNS radiation injury is a delayed, multifactorial process characterized by impaired neurogenesis, reactive gliosis, and persistent functional deficits. Mechanis...

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Literature Corpus work: a35cf0cd-433e-5539-8920-3637c773f959
DOI: 10.64898/2026.03.04.709672

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