Article

Molecular profiling of glioblastoma-derived extracellular vesicles identifies small nucleolar RNAs as candidate liquid biomarkers for radiation- induced senescence

2025-12-16

Abstract excerpt

<h4>ABSTRACT</h4> Radiation-induced senescence (RIS) in glioblastoma (GBM) is an undesirable cell fate that reduces tumor cell death and supports resistance and outgrowth. While senescence-targeting drugs are promising adjuvants, their clinical application will require proper patient selection based on post-treatment RIS burden. Current methods to evaluate senescence, however, are tissue-based, and given GBM’s di...

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Literature Corpus work: 304648a4-f74f-5d51-9a37-e619cdc09b50
DOI: 10.64898/2025.12.12.693499

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