Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effects of acute low-moderate dose ionizing radiation to human brain organoids

31 May 2023

Abstract excerpt

Human exposure to low-to-moderate dose ionizing radiation (LMD-IR) is increasing via environmental, medical, occupational sources. Acute exposure to LMD-IR can cause subclinical damage to cells, resulting in altered gene expression and cellular function within the human brain. It has been difficult to identify diagnostic and predictive biomarkers of exposure using traditional research models due to factors...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anesthesia and Neurotoxicity Research
Share to Effects of Radiation Exposure
Share to Mitochondrial Function and Pathology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37256873
DOI: 10.1371/journal.pone.0282958

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effects of acute low-moderate dose ionizing radiation to human brain organoidsPMID 37256873Read ↗

Assessment of Normal Tissue Radiosensitivity by Evaluating DNA Damage and Repair Kinetics in Human Brain OrganoidsSemantic proximity Read ↗

Temporal Mapping of Radiation-Induced Neural Injury and Mitigation in Human Cortical OrganoidsSemantic proximity Read ↗

Ionizing radiation-induced risks to the central nervous system and countermeasures in cellular and rodent modelsSemantic proximity Read ↗

Understanding Cancer Development Processes after HZE-Particle Exposure: Roles of ROS, DNA Damage Repair and InflammationSemantic proximity Read ↗

Low-Dose Ionizing Radiation Exposure, Oxidative Stress and Epigenetic Programing of Health and DiseaseSemantic proximity Read ↗

Concise Review: The Effect of Low-Dose Ionizing Radiation on Stem Cell Biology: A Contribution to Radiation RiskSemantic proximity Read ↗

Novel in vitro assay to investigate radiation induced changes in the functionality of human embryonic stem cell-derived neurospheres.Semantic proximity Read ↗

A human-specific, concerted repression of microcephaly genes contributes to radiation-induced growth defects in forebrain organoidsSemantic proximity Read ↗

A Review of Radiation-Induced Alterations of Multi-Omic Profiles, Radiation Injury Biomarkers, and CountermeasuresSemantic proximity Read ↗

Global Gene Expression Responses to Low- or High-Dose Radiation in a Human Three-Dimensional Tissue ModelSemantic proximity Read ↗

Differential redox-mitochondrial adaptation to ultra-high dose rate irradiation in astrocytes and glioma cellsSemantic proximity Read ↗

Therapeutic and space radiation exposure of mouse brain causes impaired DNA repair response and premature senescence by chronic oxidant productionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.