Article

Auto-loaded TRAIL-exosomes derived from induced neural stem cells for brain cancer therapy

2024-05-29

Abstract excerpt

Transdifferentiation (TD), a somatic cell reprogramming process that eliminates pluripotent intermediates, creates cells that are ideal for personalized anti-cancer therapy. Here, we provide the first evidence that extracellular vesicles (EVs) from TD-derived induced neural stem cells (Exo-iNSCs) are an efficacious treatment strategy for brain cancer. We found that genetically engineered iNSCs generated EVs loaded...

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Identifiers and source

Literature Corpus work: 643803a8-2854-5cff-9ac0-a46425e20535
DOI: 10.1101/2024.05.24.595724

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