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Article

Stochastic splicing and deterministic inclusion of variable exons promote diversification of <i>Down Syndrome Cell Adhesion Molecule</i> expression

2025-05-26

Abstract excerpt

Mutually alternative splicing in Down Syndrome Cell Adhesion Molecule ( Dscam ) gene of arthropods generates extraordinary molecular diversity producing tens of thousands of isoforms. From three clusters of variable exons directing homophilic interactions, one single exon is selected. Homophilic repulsion of identical isoforms directs branching of axons running in neuronal tracts, and of dendrites for generation...

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Identifiers and source

Literature Corpus work
52ab39ef-cb21-5291-82a4-583f5e2da1f4
DOI
10.1101/2025.05.21.655277
Open publication

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Stochastic splicing and deterministic inclusion of variable exons promote diversification of <i>Down Syndrome Cell Adhesion Molecule</i> expressionDOI 10.1101/2025.05.21.655277
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